Zotarolimus, also known as ABT-578 and A-179578, is an immunosuppressant. It is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier. Coronary stents reduce early complications and improve late clinical outcomes in patients needing interventional cardiology. Medtronic are using zotarolimus as the anti-proliferative agent in the polymer coating of their Endeavor and Resolute products.
咗他莫司Zotarolimus 是雷帕霉素类似物。
物化属性:
密度:1.25
沸点:1016.2°Cat760mmHg
闪光点:568.4°C
PSA:218.80000
LOGP:5.98540